Medical Laboratory Scientist (MLS) ASCP Practice Exam

The factors II (Prothrombin), VII (Proconvertin), IX (Christmas factor), and X (Stuart-Prower factor) are all associated with the coagulation process that is dependent on Vitamin K. These factors are vital for proper blood clotting and play a significant role in the extrinsic and common pathways of coagulation.

Factor II becomes active after conversion to thrombin, which is essential for converting fibrinogen into fibrin, thus forming blood clots. Factor VII is crucial for the initiation of the extrinsic pathway when activated by tissue factor. Factors IX and X are part of the intrinsic pathway (IX) and the common pathway (X) but fundamentally require Vitamin K for their synthesis in the liver. Without sufficient Vitamin K, the synthesis of these coagulation factors is impaired, leading to issues with blood clotting.

This understanding establishes that the selected answer correctly identifies these factors as Vitamin K-dependent coagulation factors, highlighting their significance in the coagulation cascade.